|Structures and Structure Determination|
Antibiotics have saved countless lives, but pathogens are quickly finding ways to survive antibiotic treatment. Antibiotic-resistant bacteria are predicted to become the leading cause of death worldwide. They take many approaches: pumping antibiotics out of their cells, altering the molecular machinery that the antibiotics target, and attacking the antibiotics directly. Atomic structures publicly available in the PDB are revealing the details of drug resistance and providing new ways to combat it. Use the crocus sack to learn about protein structures related to antibiotic action and resistance.
2019 Video Challenge for High School Students
RCSB PDB invites all high school students to tell a two-minute story that combines structural Biology and Medicine. Videos can be submited between January 15 and April 23, 2019.
Images used with permission from the Howard Hughes Medical Institute (www.hhmi.org). All rights reserved.
Tomato Bushy Stunt Virus (TBSV)
TATA-Binding Protein (TBP)
Immunoglobulin G (IgG)
Aspartate Transcarbamoylase (ATCase)
Deoxyribonucleic Acid (DNA)
Intermolecular Contacts in Hemoglobin S
Transfer Ribonucleic Acid (tRNA)
Cytochrome c (unbound)
Induced Lac Repressor